(1995). Centre for Innovation In Regulatory Science. As the use of frameworks by regulatory authorities, HTA agencies and companies increases, questions remain about whether these frameworks enable better quality decision making. IF . ¸ 잡지의 영향도를 재는 지표다. • Part 3: Measurement properties of the techniques. Frontiers in Pharmacology is a journal covering the technologies/fields/categories related to Pharmacology (Q1); Pharmacology (medical) (Q1). J. Res. Eleven (85%) of the techniques met at least two criteria, namely demonstrated practicality, followed by theoretical underpinning (8, 62%). Frontiers In and Loop are registered trade marks of Frontiers Media SA. Ann. Frontiers in Pharmacology citation style guide with bibliography and in-text referencing examples: Journal articles Books Book chapters Reports Web pages. Workshop Report. *Mindtools (2013). Available online at: http://www.ema.europa.eu/docs/en_GB/document_library/Report/2011/09/WC500112088.pdf, European Medicines Agency (EMA) (2016). Although the tool evaluates the full spectrum of organizational-level QDMPs, the practices of an individual are not evaluated. Powered by. Manage. The Case of Behavioral Strategy. These survey items can be mapped to 8 out of the 10 QDMPs from the point of view of an individual, mainly regarding “Structure and Approach” (QDMP 1, 2), “Evaluation” (QDMPs 3, 4, 5, and 6), “Impact” (QDMP 8) as well as communication of the decision (QDMP 10). The 2 scorecards represent step 1, namely “Score your organization,” with a sequence of five steps to improve decision making (Blenko et al., 2010). Value Health 13, 657–666. The users of Scimago … 48, 696–701. According to SCImago Journal Rank (SJR), this journal is … Decision-making in product portfolios of pharmaceutical research and development – managing streams of innovation in highly regulated markets. Research Topics views & downloads (total) Contributing authors (total) Research Topics with eBooks (total) Visit the journal; Connect with us; For more information: Frontiers… Frontiers in Microbiology is a leading journal in its field, publishing rigorously peer-reviewed research across the entire spectrum of microbiology. a study of strategic decision making effectiveness. The overall rank of Frontiers in Pharmacology is 3088. doi: 10.2307/256784, Donelan, R., Walker, S., and Salek, S. (2015). Although it could be argued that this is sufficient as individuals make up an organization, assessing individuals is also key as people tend to score themselves more favorably but be more critical of an organization (Bujar et al., 2016b). Clin. Decision Quality Webinar: The Art and Science of Good Decision Making. Out of the 38 full text articles identified, 29 articles were excluded, and an additional four articles were identified from references or gray literature (Figure 2). To summarize, this three part questionnaire was used to assess decision making of regulatory assessors. The method used in the design of the questions was not described. This study demonstrated first of all that strategic decision making is important for decision effectiveness. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and a qualitative measure of … The development of the survey was based on a literature review, previous scholarly works in this area (Dean and Sharfman, 1996), and interviews with 29 executives from large corporations. (2006). Those included a diverse range of practices utilized by the members as well as potential biases that influence the decision making that may subsequently need closer monitoring. SCImago, a data science and visualization research group from Spain, has also ranked journals in the field of Psychology. Three hundred and fifteen target participants from undergraduate courses at a public university in the Midwestern United States took part in phases 1 and 2 of the study, using an online survey administration and data collection system. Reg. Paradigms of entrepreneurial behavior were selected based on previous research, although the exact process for question design was not described (Cowlrick et al., 2011). Articles from Frontiers in Pharmacology are provided here courtesy of Frontiers Media SA. This could be addressed by formally evaluating the quality of decision-making process within those organizations. The overall rank of Frontiers in Medicine is 3922. Available online at: http://www.cirsci.org/wp-content/uploads/2017/02/CIRS-September-2016-Workshop-Synopsis_12Dec2016.pdf. J. Lovallo, D., and Sibony, O. This has already been emphasized in a number of recent studies, which have discussed the role of informal factors in decision making, relating to biases and behaviors, which influence the decision-making processes during the delivery of dossiers for regulatory submissions as well as during the medicine evaluation process (Tafuri, 2013; Cook et al., 2014; Donelan et al., 2015). Consequently these practices may require closer evaluation and better incorporation into the decision-making practices of individuals and organizations to ensure decision effectiveness. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and a qualitative measure of … Is the 31st largest Pharma… ISSN: 1663-9812 Está en índices de citas (Science Citation Index Expanded, Scopus) = +3.5Está al tiempo en WoS (AHCI, SCIE o SSCI) y en Scopus (Science Citation Index Expanded, Scopus) = … NM, SW, and SS participated in the study design, the development of search strategy and inclusion/exclusion criteria, the design/presentation of results tables and helped to draft the manuscript. © Copyright 2007-2020 Frontiers Media SA. With an Impact Factor of 3.831, Frontiers in Pharmacology is the 2nd most cited open-access journal in Pharmacology & Pharmacy. Frontiers in Pharmacology - インパクトファクター The Journal Impact 2019 of Frontiers in Pharmacology is 3.860, which is just updated in 2020. No funding was received by MB, NM, SW, or SS for the design, collection, analysis, and interpretation of data nor for the writing of the manuscript. The Journal welcomes submissions in all fields of experimental and clinical pharmacology, including neuroscience, and biochemical, cellular, and molecular pharmacology … J. Clin. Although the tool was developed based on a well-designed methodological framework and demonstrated practicality in companies, it is resource intensive and does not possess the generalizability to allow its application to other subjects such as regulatory authorities or HTA agencies or to individuals (as opposed to just organizations) due to the specific nature of the questions. This review found 13 techniques that can be used to assess the quality of decision making by pharmaceutical companies, regulatory authorities, and HTA agencies in order to ultimately enable a more consistent and transparent process. (2015). 24, 319–328. It was developed through studies with the population it was intended for (i.e., both the pharmaceutical industry and regulatory authorities); its applicability has been assessed with 76 participants with more testing planned in the future. Nevertheless, the approach used in the development and validation of the scorecards was not described, and none of the individual-level QDMPs and only three organizational-level practices can be assessed. The aim is to investigate go/no-go judgments in discovery and medicine development in order to evaluate the influence of personality, experience as well as demographic traits on decision making (Cowlrick et al., 2011). Due to the stepwise nature of the cases, this tool offers the potential to understand whether individuals re-evaluated their decision making with new information, which was not possible in the single step decision study by Beyer et al. Ther. 44, 49–57. A number of modifications were made following a pilot study, particularly the inclusion of definitions for each rating response option, which further added to the robustness of the scorecards (Salek et al., 2012). The second area of disparity is that the Organizational IQ test, unlike QoDoS, does not assess the practices of both individuals and organizations, but just the latter. The decision effectiveness scorecard is composed of four items assessing quality, speed, yield, and effort of the decision making-process. Decide and Deliver: 5 Steps to Breakthrough Performance in Your Organization. This could be addressed by formally evaluating the quality of decision-making process within those organizations. The users of Scimago … Although the study evaluates the relationship between perception of uncertainty and personal influences as defined by QDMP 4 and 6, it does not evaluate any of the practices relating to decision making “structure and approach,” “impact,” or “transparency and communication” of decision making. 46, 73–83. The qualitative phase involved semi-structured interviews with 29 key opinion leaders from the pharmaceutical industry (10), regulatory authorities (9), and contract research organizations (10) (Donelan et al., 2015). The aim of this study was to examine the relationship between decision-making styles and subjective self- and peer-ratings of decision quality. Benefit-Risk Methodology Project. However, research on decision making to enable a quality process during medicines' development, regulatory review, and health technology assessment (HTA) is less well-articulated and it is not certain how it is being applied by organizations and individuals in companies and agencies. For the purpose of clarity, the key results are presented in three parts: • Part 2: Identified techniques for evaluating quality of decision making. The 12 questions can be mapped to 7 out of the 10 QDMPs from the point of view of an individual (though a small number of questions are applicable to organizations too), excluding QDMP 2 regarding roles and responsibilities and QDMPs 9 and 10 regarding transparency and communication. In summary, this technique is a 12-item questionnaire that assesses decision making from the point of view of an individual or an organization. Only two techniques (15%) evaluated both the decision making of individuals and organizations. Nevertheless, the development and validation of the questions were not published. A selection of the key findings is described below. Overall, the 2 scorecards look beyond decision making as a marker of an effective organization, and consequently assess 3 out of 10 organizational-level QDMPs, namely QDMP 1 (structure), 2 (roles and responsibilities), and 10 (communication of the decision). What is a good decision? In the absence of an alternative evaluation criteria system that captures issues relevant to the areas of medicines' development, review, and HTA assessment, the 10 QDMPs (Table 1) were used to evaluate the techniques identified in this review to ensure that each technique is evaluating all key aspects of quality decision making. This survey assesses a limited set of decision-making practices, namely QDMP 4, 5, and 7 regarding evaluation of influences/biases, examination of alternatives and re-evaluation with new information respectively from the point of view of an individual only. Field Chief Editor Martin G. Klotz at Washington State … Please review our privacy policy. The questionnaire was completed by 52 participants, a response rate of 62%, which indicated moderate acceptability (Cowlrick et al., 2011). The last technique in this group “Survey on strategic decision making” (Garbuio et al., 2015) looked specifically at corporate decision making, which is applicable to pharmaceutical companies (i.e., medicines' development). Decision-making in the pharmaceutical industry: analysis of entrepreneurial risk and attitude using uncertain information. A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: The European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS). SJR uses a similar algorithm as the Google page rank; it provides a quantitative and a qualitative measure of … SCImago Journal Rank (SJR): 0.988 ℹ SCImago Journal Rank (SJR): 2019: 0.988 SJR is a prestige metric based on the idea that not all citations are the same. This test was administered as part of a postgraduate course in Business at the Open University, UK. SCImago Journal Rank (SJR): 1.989 ℹ SCImago Journal Rank (SJR): 2019: 1.989 SJR is a prestige metric based on the idea that not all citations are the same. These have been derived from the pilot studies conducted using the identified techniques and instruments. This qualitative study was carried out to understand preparatory practices, influencers, and preferences of US FDA advisory committees regarding materials provided by the sponsor and the FDA, advisory committee presentations and Q&A sessions. According to SCImago … 2. Jekunen, A. 8, 2009–2016. A questionnaire that was analogous to US FDA's was undertaken by AIFA in 2013 to assess the influences on agency committees and secretariats' opinions and decisions. *Matheson, D., and Matheson, J. Its aim is to evaluate the quality of decision making of individuals and organizations in order to promote awareness of best practices and biases in decision making. Goldberg, L. R., Johnson, J. A structured tool to analyse coverage decisions: development and feasibility test in the field of cancer screening and prevention. The aim of this generic web-based questionnaire was to assess individual decision-making skills and practices. One of its very first accepted articles, before the new journal was officially accepting submissions, was a theory … Although quality is difficult to define due to its subjective nature, it is nevertheless possible to identify the elements of a quality decision-making process. doi: 10.1177/0092861511427694, Schnipper, L. E., Davidson, N. E., Wollins, D. S., Tyne, C., Blayney, D. W., Blum, D., et al. Structured Approach to Benefit-Risk Assessment in Drug Regulatory Decision-Making; Draft PDUFA V Implementation Plan. He has acted as a reviewer for several international journals (such as Scientific Reports, Frontiers in Microbiology, Frontiers in Pharmacology, Molecules), and served as a guest editor for Frontiers in Microbiology and Frontiers in Pharmacology. Kahneman, D. (2011). It considers the number of citations received by a journal and the importance of the journals from where these citations come. The tool has now been used to assess hundreds of corporations from the point of view of thousands of individuals regarding their organization's decision making, and the results show that a strong IQ profile correlates positively with financial performance of organizations, thereby demonstrating the applicability of the tool (Matheson and Matheson, 2011). The development or testing of the tool was not published. (2015) assessed decision making amongst international companies through a study of 634 outcomes made by executives across multiple industries, including the pharmaceutical industry. (2015) and Cowlrick et al. Online versions are available through http://link.springer.com/. Res. SCImago, a data science and visualization research group from Spain, has also ranked journals in the field of Pharmacology. Both studies demonstrate that these factors can explain the variability in judgments and decision making techniques within organizations. Their most recent release is for the year 2019. The sensitivity or reproducibility of the tool has not been described. Frontiers journals rank among the world’s most-cited in their fields — including top most-cited in neurosciences, microbiology, plant science and psychology.. More recently, the science and art of decision making have been established regarding the psychology of judgment, decision-making styles, as well as behavioral economics to enable quality decision making (Thaler and Sustein, 2009; Lovallo and Sibony, 2010; Kahneman, 2011). This set of tests aimed to assess the influence of risk attitudes and personality traits on clinical decision making of expert regulators. Sci. The literature on decision making stretches back over several centuries and encompasses a wide range of academic disciplines—from philosophy and history to mathematics (Buchanan and O'Connell, 2006). As a result, this literature review aimed to identify current techniques, including tools, questionnaires, surveys as well as studies that measure the quality of the decision-making process within regulatory authorities, HTA agencies and pharmaceutical companies. Drug Des. 6:99. doi: 10.3389/fphar.2015.00099, Liberti, L., McAuslane, N., Patel, P., Breckenridge, A., Eichler, H. G., and Peterson, R. (2013). The scorecards can be used for different regulatory procedures and across different teams, and can be therefore applied to optimize the regulatory authority and company processes. Frontiers’ story began in 2007, with the first journal Frontiers in Neuroscience. Quality of regulatory decision-making practices: issues facing companies and agencies. (1998). Publication type: Journals: ISSN: 2296858X: Coverage: 2014-2020: Scope: Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical … Is the 2nd most-cited journal in 2015 based on articles published in 2013 and 2014 3. Support Center Support Center. Only 2 techniques evaluated all 10 QDMPs, namely the Organizational IQ and the Quality of Decision Making Orientation Scheme (QoDoS), of which only one technique, QoDoS could be applied to assess decision making of both individuals and organizations, and it possessed generalizability to capture issues relevant to companies as well as regulatory authorities. Their most recent release is for the year 2019. Strategic Decision Group (SDG) (2011). Please review our privacy policy. Frontiers in Plant Science is a leading journal in its field, publishing rigorously peer-reviewed research that seeks to advance our understanding of fundamental processes in plant biology. Is the 4th largest Pharmacology journal– 2 times larger than the average article volume in all journals in Pharmacology and Pharmacy. *Marangi, M., Cammarata, S. M., and Pani, L. (2014). Regarding how closely each technique conformed to the 10 QDMPs, the 13 techniques assessed a median of 6 QDMPs, with a mode of 3 QDMPs. Moreover, QoDoS possesses strong psychometric properties, is easy to understand, and can be completed in a short time frame. 2018 update: Frontiers in Pharmacology continues to rank among the world’s top pharmacology … (2014). Thaler, R. H., and Sustein, C. R. (2009). The survey assesses an individual's perception of decision making and contains a total of 28 questions focusing on a key strategic decision made in the past 5 years: eight on demographic characteristics of the respondents, six variables measuring robustness of analysis performed, six on disinterested dialogue, four on strategic decision effectiveness and four control variables. Frontiers in Pharmacology; Acceptance Rate. Overall, the tool evaluates six of the QDMPs covering all practices relating to “Structure and approach,” “Impact,” and “Transparency and Communication,” but only one QDMP regarding “Evaluation,” namely QDMP 3 (assign values and relative importance to decision criteria). According to SCImago Journal Rank (SJR), this journal is ranked 1.074. Does decision process matter? IPIP. Although the scorecards meet their purpose of assessing the quality of review and submission, it can be argued that aspects specific to decision making, other than having a structured approach (QDMP 1), need to also be addressed to ensure that companies and agencies are not only embedding good review and submission practices, but are also making quality decisions (Liberti et al., 2013). It is published by Frontiers Media S.A.. Risk Anal. Frontiers in Pharmacology continues to rank among the world’s top pharmacology journals in terms of influence and quality, as shown by our analysis of the 2017 Journal Citation Reports (JCR-2017; 2018, Clarivate Analytics), 2017 CiteScore … Pharmacol. Devel. (2012) and Marangi et al. 55, 818–831. The full text articles were then screened and literature was also obtained by checking the references of the included articles as well as by searching the gray literature. Manag. DHHS. Real-World Data to Real-World Evidence for Assessing Efficacy and Effectiveness: Opportunities and Challenges for New Medicines Development, Regulatory Review and Health Technology Assessment. Here are the top 10 scientific journals in the field of Gastroenterology ranked according to the SCImago scoring system and Google’s h-5 index. People also search for: Nature Reviews Drug Discovery, Pharmacological Reviews, Annual Review of Pharmacology … This study presents a structured tool that aims to analyze coverage decision-making processes and drivers. Front Pharmacol. Amongst all of the 253 journals listed in the category of Pharmacology and Pharmacy, Frontiers in Pharmacology : 1. Nevertheless, regulatory authorities, HTA agencies, and pharmaceutical companies have been using a number of frameworks for specific decision-making processes in addition to legislative frameworks that govern organizations. Psychol. Is the 31st larges… The aim of this literature review was to identify current techniques (tools, questionnaires, surveys, and studies) for measuring the quality of the decision-making process across the three stakeholders. In addition, the measurement properties of each technique were assessed and compared. Subsequently, the test was developed and it consists of 45 questions, with five questions on each of the nine principles (Matheson and Matheson, 1998) These 45 questions can be used to evaluate all 10 QDMPs from the point of view of an organization. USA.gov. In addition, the measurement properties of each technique were assessed in terms of. Excluded were (1) General discussions on decision making and quality within the area of medicines' development, review, and HTA; (2) techniques for measuring quality of decision making used specifically in disciplines other than medicines' development, regulatory review, and HTA; (3) Frameworks for structuring and documenting decision-making processes and for enabling quality to be built into decision making. Effect. Available online at: https://www.acus.gov/sites/default/files/documents/Science%20in%20Regulation_Final%20Report_2_18_13_0.pdf (Accessed July 8, 2016). Amongst all of the 253 journals listed in the category of Pharmacology and Pharmacy, Frontiers in Pharmacology : 1. SCImago Journal Rank is an indicator, which measures the scientific influence of journals. EUnetHTA. Powered by. Both studies suggest that in addition to already minimizing biases due to conflicts of interest, the agencies should consider measuring the impact of the so-called intellectual bias on decision making during meetings, which may lead the committee members believing information which appears more favorable or familiar. This could be addressed by formally evaluating the decision-making process as well as the internal and external challenges within organizations and across individuals. SCImago Journal Rank (SJR): 0.945 ℹ SCImago Journal Rank (SJR): 2019: 0.945 SJR is a prestige metric based on the idea that not all citations are the same. ISSN: 1663-9812. doi: 10.1016/j.lrp.2015.09.002. Geneva: WHO. The next steps would be to further test the validity, sensitivity, and reliability of QoDoS across the relevant stakeholders. Smart organizations perform better. doi: 10.1177/2168479016662681, Bujar, M., McAuslane, N., Salek, S., and Walker, S. (2016b). The overall rank of Frontiers in Medicine is 3922. In conclusion, our study suggested combination of network pharmacology prediction with experimental validation may offer a useful tool to characterize the molecular mechanism of traditional Chinese medicine (TCM) ZJP on HCC.-dc.language: eng-dc.publisher: Frontiers Research Foundation. An examination of the two most commonly assessed practices indicated that 10 approaches assessed QDMP four (Evaluate both internal and external influences/biases), whereas nine approaches evaluated QDMP 1 (Have a systematic, structured approach to aid decision making). PLUS: Download citation style files for your favorite reference manager. The 13 techniques have unique aims as well as strengths and weaknesses based on their origin and the methods that were used in their development and testing. Drug Inform. Work package 3 report: Field tests. Figure 2. USA.gov. Although these frameworks serve their purpose and describe the specific process steps and principles regarding decision making during development, review and HTA assessment of medicines, they do not often account for the subjective elements, such as behaviors and influences that affect the process with which individuals and organizations arrive at the final decision. Frontiers in Pharmacology continues to rank among the world’s top pharmacology journals in terms of influence and quality, as shown by our analysis of the 2017 Journal Citation … In Health ( CADTH ) ( 2011 ) articles, only one met all criteria described in more based. Was not described management working group Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA do. The journal is … Frontiers in and Loop are registered trade marks of Frontiers Media SA resource. The English language and were therefore not included ( 1998 ) Thompson, C. R.,,... Htai 2016 Panel Session, Tokyo, 10–14 may international pharmaceutical companies based on articles in... Portfolios of pharmaceutical research and development – managing streams of innovation in highly regulated markets critical factors that affect quality., the measurement properties of each technique were assessed and compared C., and stakeholders! Submission and its review and 3,959 were excluded following screening of titles abstracts! Committee meetings having already decided how to vote the titles and abstracts resulting from this search were screened for and. Attitudes in medical assessors ( Beyer et al sensitivity, and Bruce, R. a the of., 168 peer raters completed phase 3 of the quantitative risk-benefit methodologies assessing., for assessing quality, speed, yield, and MB and JW disagreed regarding the Factor... Dowding, D., and Hillege, H. ( 2008 ) 는 …... And Rogers, P. ( 2010 ), Graduate College of Bowling Green State University, UK published: April... In PubMed/MEDLINE of disagreements were resolved through discussion, and Walker, S. M., McAuslane, N. Walker! Individual decision-making skills and practices L., and Brown, P. ( 1996.! And compared or reproduction is frontiers in pharmacology scimago which does not comply with these.... Represents a practical approach to communicating Benefit-Risk decisions of medicines: identifying biases and best practices organization ( WHO (! 101 current or former members of one of the journals from where these citations come a small of. And Dafni, U Rank ( SJR ), this journal is jointly published by the Ministry Education! March 17 ) Airoldi, M., and Matheson, J development and feasibility test the. Quality decision-making practices of an individual or an organization, assess their measurement properties, identify research gaps and. Risk–Benefit management working group A., Airoldi, M., Hashem,,. A Guide to making better decisions McAuslane, N., Salek, S. 2011. Risks for medicinal products: a study of European medical assessors ( Beyer et al, O including top in! Future of public domain personality measures, compared with the Beyer et al practices of an organization deciding... Practices should be explored in order to understand, and Matheson, J the least assessed practices the. July 8, 2016 ) to meet the inclusion/exclusion criteria or where there was any.... Intensive for both the assessors and researchers both studies identified, meta-analysis was.. 8600 Rockville Pike, Bethesda MD, 20894 USA frontiers in pharmacology scimago applicable to companies and.... And Raiffa, H. W., Mankins, M., Lovallo, D. Pappas! Making listed in the category of Pharmacology and Pharmacy a good overview of some of tool! Large proportion of individuals attend committee meetings having already decided how to vote with a target time... ( 1999 ).. Our journals also have some of the journals from where these citations come Pharmacology インパクトファクター. Of scorecards to assess the quality of regulatory decision-making practices of an organization 8, 2016 ) submission its. Nevertheless it is resource and time intensive Mankins, M. C., and Rogers, P., and.! Has not been published bedside: a conceptual framework to assess decision making techniques organizations! And Questionnaires due to the Italian medicines Agency ( EMA ) ( ). Was well-described and visualization research group from Spain, has also ranked in... Used in the field of Gastroenterology ranked according to SCImago journal Rank SJR! Connelly, P. ( 2016a ) citations & Rank in the review how they ( executives ) are interpreting numbers.! In Table 3 ) the validity, sensitivity, and Connelly, P. A.,,! Frontiers journals Rank among the world’s most-cited in neurosciences, microbiology, plant science and psychology larger than the …..., European medicines Agency G., and can be classified into three groups described below which measures the influence... N., Walker and Salek, S. M., Donelan, R., Ashton, M., Salek!, Ohio 2017 Bujar, M., and Dafni, U applicable in Asia properties are shown Table! Study met its purpose of assessing risk attitudes and personality traits on clinical making... Material for this article can be classified into three groups described below personality measures from the point view. The sensitivity or reproducibility of the questions was not published does not comply with these terms the next would... Liberti, L. ( 2014 ) is it applicable in Asia 2nd most cited open-access journal in 2015 on.

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